961 research outputs found

    A Method for Solving a Class of Multiple-Criteria Analysis Problems

    Get PDF
    AMS subject classification: 90C29.The paper proposes an interactive method solving the multiple criteria choice problem (MCCP) with a large number of discrete alternatives and a small number of quantitative criteria. The decision maker (DM) sets his preferences in terms of desired directions of improving or relaxing of the criteria. On this base the so called reference cone is constructed. A small subset of relatively closed alternatives is defined according to this cone and to the maximal deterioration of the criteria values at each iteration. This subset is evaluated by the DM, who selects the most preferred alternative or enters his/her new preferences. The method suggested has user-friendly dialog. It enables the DM to explore the set of alternatives comparatively quickly and easy. The method is included in a DSS. It is tested by a number of real multiple criteria choice problems

    Long-term variability of CO2 and O in the Mars upper atmosphere from MRO radio science data

    Get PDF
    We estimate the annual variability of CO2 and O partial density using approximately 6years of Mars Reconnaissance Orbiter (MRO) radio science data from August 2006 to January 2012, which cover three full Martian years (from the northern hemisphere summer of 28 to the northern hemisphere summer of 31). These two elements are the dominant species at the MRO periapsis altitude, constituting about 70-80% of the total density. We report the recovered annual cycle of CO2 and the annual and seasonal cycle of O in the upper atmosphere. Although no other observations are available at those altitudes, our results are in good agreement with the density measurements of the Mars Express Spectroscopy for Investigation of Characteristics of the Atmosphere of Mars, which uses stellar occultations between 60 and 130km to determine the CO2 variability, and with the Mars Global Reference Atmospheric Model 2010 for the O annual and seasonal variabilities. Furthermore, the updated model provides more reasonable MRO drag coefficients (CD), which are estimated to absorb mismodeling in the atmospheric density prediction. The higher content of dust in the atmosphere due to dust storms increases the density, so the CDs should compensate for this effect. The correlation between the drag coefficient and the dust optical depth, measured by the Mars Odyssey Thermal Emission Imaging System (THEMIS) instrument, increases from 0.4 to 0.8 with the a priori and adjusted models, respectively. The trend of CDs not only confirms a substantial improvement in the prediction of the atmospheric density with the updated model but also provides useful information for local dust storms, near MRO periapsis, that cannot be measured by the opacity level since THEMIS does not always sample the southern hemisphere evenly

    Multi-omic analyses in Abyssinian cats with primary renal amyloid deposits

    Get PDF
    The amyloidoses constitute a group of diseases occurring in humans and animals that are characterized by abnormal deposits of aggregated proteins in organs, affecting their structure and function. In the Abyssinian cat breed, a familial form of renal amyloidosis has been described. In this study, multi-omics analyses were applied and integrated to explore some aspects of the unknown pathogenetic processes in cats. Whole-genome sequences of two affected Abyssinians and 195 controls of other breeds (part of the 99 Lives initiative) were screened to prioritize potential disease-associated variants. Proteome and miRNAome from formalin-fixed paraffin-embedded kidney specimens of fully necropsied Abyssinian cats, three affected and three non-amyloidosis-affected were characterized. While the trigger of the disorder remains unclear, overall, (i) 35,960 genomic variants were detected; (ii) 215 and 56 proteins were identified as exclusive or overexpressed in the affected and control kidneys, respectively; (iii) 60 miRNAs were differentially expressed, 20 of which are newly described. With omics data integration, the general conclusions are: (i) the familial amyloid renal form in Abyssinians is not a simple monogenic trait; (ii) amyloid deposition is not triggered by mutated amyloidogenic proteins but is a mix of proteins codified by wild-type genes; (iii) the form is biochemically classifiable as AA amyloidosis.Peer reviewe

    Postharvest loss in the supply chain for vegetables - The case of tomato, yardlong bean, cucumber and chili in Lao PDR

    Get PDF
    AVRDC Publication 06-684Christian Genova II, Katinka Weinberger, Thongsavath Chanthasombath, Bouthsakone Inthalungdsee, Kham Sanatem, Kethongsa Somsa

    Postharvest loss in the supply chain for vegetables - The case of tomato, yardlong bean, cucumber and chili in Lao PDR

    Get PDF
    AVRDC Publication 06-684Christian Genova II, Katinka Weinberger, Thongsavath Chanthasombath, Bouthsakone Inthalungdsee, Kham Sanatem, Kethongsa Somsa

    Humoral immune response to different routes of myxomatosis vaccine application

    Get PDF
    [EN] The aim of our study was to monitor the dynamics of the serological response to different application routes of live attenuated myxomatosis vaccine. The study included 42 Californian breed rabbits, aged 3 mo, of both sexes. They were separated into 7 groups: 6 experimental and 1 control. All experimental groups were vaccinated on day 0 with a single dose of myxomatosis vaccine (min 103.3 tissue culture infective dose 50 [TCID50], max 105.8 TCID50). Three of the groups were injected with monovalent attenuated myxomatosis vaccine using different types of application: intradermal (i.d.), intramuscular (i.m.) and subcutaneous (s.c.). The other 3 groups were injected with bivalent attenuated vaccine against myxomatosis and rabbit haemorrhagic disease; again the routes of administration were i.d., i.m. and s.c.. There were no clinical signs or serious side effects after vaccination. The serological response was evaluated on days 7, 15 and 30 with a monoclonal antibody based-competition enzyme-linked immunosorbent assay (cELISA). More rapid and potent humoral response was detected in groups with i.d. inoculation in comparison to i.m. and s.c. routes. Vaccination with monovalent vaccine against myxomatosis induced higher antibody titre in comparison to bivalent vaccine. Our study showed that the vaccine application route and the type of vaccine used influence the speed and intensity of antibody response.Manev, I.; Genova, K.; Lavazza, A.; Capucci, L. (2018). Humoral immune response to different routes of myxomatosis vaccine application. World Rabbit Science. 26(2):149-154. doi:10.4995/wrs.2018.7021SWORD149154262Alfonso M., Pagès-Manté A. 2003. Serological response to Myxomatosis vaccination by different inoculation systems on farm rabbits. World Rabbit Sci. 2003, 11: 145-156. https://doi.org/10.4995/wrs.2003.504Barcena J., Morales M., Vázquez B., Boga J., Parra F., Lucientes J., Pagès-Manté A., Sánchez-Vizcaino J., Blasco R., Torres J. 2000. Horizontal Transmissible Protection against Myxomatosis and Rabbit Hemorrhagic Disease by Using a Recombinant Myxoma Virus. J. Virol., 74, 1114-1123.Bertagnoli S., Gelfi J., Gall G., Boilletot E., Vautherot J., Rasschaert D., Laurent S., Petit F., Boucraut-Baralon C., Milon A. 1996. Protection against myxomatosis and rabbit viral hemorrhagic disease with recombinant myxoma viruses expressing rabbit hemorrhagic disease virus capsid protein. J. Virol., 70: 5061-5066.Best S., Kerr P. 2000. Coevolution of Host and Virus: The Pathogenesis of Virulent and Attenuated Strains of Myxoma Virus in Resistant and Susceptible European Rabbits. Virology, 267, 36-48. https://doi.org/10.1006/viro.1999.0104Bhanuprakash V., Hosamani M., Venkatesan G., Balamurugan V., Yogisharadhya R., Singh R. 2012. Animal poxvirus vaccines: a comprehensive review Expert Rev. Vaccines, 11, 1355-1374. https://doi.org/10.1586/erv.12.116Calvete C., Estrada R., Lucientes J., Osacar J., Villafuerte R., 2004. Effects of vaccination against viral haemorrhagic disease (VHD) and myxomatosis on long-term mortality rates of European wild rabbits. Vet. Rec., 155: 388-392.Dalton K., Nicieza I., Gullón J., Inza M., Petralanda M., Arroita Z., Parra F. 2012. Analysis of Myxomatosis outbreaks on Spanish rabbit farms. In Proc.: 10th World Rabbit Congress, September 3 - 6, 2012, Sharm El- Sheikh, Egypt, 1203-1207.Dalton K., Nicieza I., de Llano D., Gullón J., Inza M., Petralanda M., Arroita Z., Parra F. 2015. Vaccine breaks: Outbreaks of myxomatosis on Spanish commercial rabbit farms. Vet. Microbiol., 178, 208-216. https://doi.org/10.1016/j.vetmic.2015.05.008Dan M., Baraitareanu S., Danes D., 2014. Serosurveillance of Myxomatosis by Competitive ELISA. Bulletin UASVM Veterinary Medicine. 71, 266-267.Day M., Fenner F., Woodroofe G., McIntyre G.A. 1956. Further studies on the mechanism of mosquito transmission of Myxomatosis in the European rabbit. J. Hyg. Cambridge, 54:258-283.Farsang A., Makranszki L., Dobos-Kovacs M., Virag G., Fabian K., Barna T., Kuclsar G., Kucsera L., Vetesi F. 2003. Occurrence of atypical myxomatosis in central Europe: clinical and virological examinations. Acta Vet. Hung., 51, 493-501. https://doi.org/10.1556/AVet.51.2003.4.7Fenner F., Ratcliffe F. 1965. Myxomatosis. Cambridge University Press, Cambridge, England. Ferreira C., Ramírez E., Castro F., Ferreras P., Alves P., Redpath S., Villafuerte R. 2009. Field experimental vaccination campaigns against myxomatosis and their effectiveness in the wild. Vaccine, 27: 6998-7002. https://doi.org/10.1016/j.vaccine.2009.09.075Jeklova E., Leva L., Matiasovic J., Kovarcik K., Kudlackova H., Nevorankova Z., Psikal I., Faldyna M. 2007. Characterisation of immunosuppression in rabbits after infection with myxoma virus, Vet. Microbiol., 129: 117-130. https://doi.org/10.1016/j.vetmic.2007.11.039Kerr P.J. 1997. An ELISA for Epidemiological Studies of Myxomatosis: Persistance of Antibodies to Myxoma Virus in European Rabbits (Oryctolagus cuniculus). Wildlife Res., 24: 53-65.https://doi.org/10.1071/WR96058Kerr P.J. 2012. Myxomatosis in Australia and Europe: A model for emerging infectious diseases. Antivir. Res., 93: 387-415. https://doi.org/10.1016/j.antiviral.2012.01.009Kim, Y.C., Jarrahian, C., Zehrung, D., Mitragotri, S., Prausnitz , M.R. 2012. Delivery Systems for Intradermal Vaccination. Curr. Top. Microbiol., 351: 77-112. https://doi.org/10.1007/82_2011_123King A., Adams M., Carstens E., Lefkowitz E. 2012. Virus Taxonomy. Classification and Nomenclature of Viruses. Ninth Report of the International Committee on Taxonomy of Viruses, 291-309.Lavazza A., Graziani M., Tranquillo V.M., Botti G., Palotta C., Cerioli M., Capucci L. 2004. Serorological evaluation of the immunity induced in commercial rabbits by vaccination for Myxomatosis and RHD, In Proc.: 8th World Rabbit Congress, September 7-10, 2004, Puebla, Mexico, 569-575.Le Normand B., Chatellier S., Devaud I., Delvecchio A., Lavazza A., Capucci L. 2015. Evaluation de l'immunité humorale consécutive à la vaccination avec Dervaximyxo SG33 chez des lapines reproductrices vaccinées à différents stades du cycle productif. 16e Journées de la Recherche Cunicole. Le Mans, France. 17-20.Lemiere S. 2000. Combined vaccination against myxomatosis and VHD: an innovative approach, In: 7th World Rabbit Congress, Valencia, 4-7th July, Spain, World Rabbit Sci., 8 suppl 1. Vol. B:289-297.Levin C., Perrin H., Combadiere B. 2015. Tailored immunity by skin antigen-presenting cells. Hum. Vacc. Immunother., 11: 27-36. https://doi.org/10.4161/hv.34299Marlier D. 2010. Vaccination strategies against myxomavirus infections: are we really doing the best? Tijdschr Diergeneesk., 135: 194-198.Marlier D., Mainil J., Boucraut-Baralon C., Linden A., Vindevogel H. 2000. The efficacy of two vaccination schemes against expérimental infection with a virulent amyxomatous or a virulent nodular myxoma virus strain. J. Comp. Path. Vol. 122, 115-122. https://doi.org/10.1053/jcpa.1999.0346Marshall I., Regnery C. 1960. Myxomatosis in a California brush rabbit (Sylvilagus bachmani). Nature, 188: 73-74. http://doi.org/10.1038/188073b0Morimoto M. 2009. General Physiology of Rabbits. In: Houdebine LM., Fan J. (eds) Rabbit Biotechnology. Springer, Dordrecht. OIE. 2014. Myxomatosis. Chapter 2.6.1. (NB: Version adopted in May 2014). Manual of Diagnostic Tests and Vaccines for Terrestrial Animals http://www.oie.int/fileadmin/Home/fr/Health_standards/tahm/2.06.01_MYXO.pdf Accessed June 2018.Panchanathan V., Chaudhri G., Karupiah G. 2008. Correlates of protective immunity in poxvirus infection: where does antibody stand? Immunol. Cell Biol., 86, 80-86. https://doi.org/10.1038/sj.icb.7100118Rouco C, Moreno S, Santoro S. 2016. A case of low success of blind vaccination campaigns against myxomatosis and rabbit haemorrhagic disease on survival of adult European wild rabbits. Prev. Vet. Med., 133: 108-113. https://doi.org/10.1016/j.prevetmed.2016.09.013Spibey N., McCabe V., Greenwood N., Jack S., Sutton D., van der Waart L. 2012. Novel bivalent vectored vaccine for control of myxomatosis and rabbit haemorrhagic disease. Vet. Rec., 170: 309. http://dx.doi.org/10.1136/vr.10036

    Text-based Editing of Talking-head Video

    No full text
    Editing talking-head video to change the speech content or to remove filler words is challenging. We propose a novel method to edit talking-head video based on its transcript to produce a realistic output video in which the dialogue of the speaker has been modified, while maintaining a seamless audio-visual flow (i.e. no jump cuts). Our method automatically annotates an input talking-head video with phonemes, visemes, 3D face pose and geometry, reflectance, expression and scene illumination per frame. To edit a video, the user has to only edit the transcript, and an optimization strategy then chooses segments of the input corpus as base material. The annotated parameters corresponding to the selected segments are seamlessly stitched together and used to produce an intermediate video representation in which the lower half of the face is rendered with a parametric face model. Finally, a recurrent video generation network transforms this representation to a photorealistic video that matches the edited transcript. We demonstrate a large variety of edits, such as the addition, removal, and alteration of words, as well as convincing language translation and full sentence synthesis

    Market analysis of fresh vegetables in Solomon Islands

    Get PDF
    Christian Genova, Pepijn Schreinemachers and Victor Afari-Sef
    • …
    corecore